DATE: 26.05.2012
AUTHOR: ringcandnigh
10-keto-hydrocodone
Inhibition of Cytochrome P450 2D6 Metabolism of Hydrocodone to.
Abstract. Enzymatic conversion of hydrocodone to hydromorphone is catalyzed by cytochrome P450 2D6, which is inactive in about 7% of Caucasians [poor.
Preparation of 10-Keto Morphinans by Benzylic Oxidation - Patent.
After workup, concentration, and column chromatographic purification (0 to 5% MeOH in CHCl 3), 2.66 g of 10-keto hydrocodone (8.49 mmol, 61% yield) was obtained.
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10-keto-hydrocodone Inhibition of Cytochrome P450 2D6 Metabolism of Hydrocodone to.
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